Campylobacter bacteria are very sensitive to chlorine used for water purifying. Due to time-consuming and expensive diagnostics, testing for Campylobacter infections is performed relatively rare. It is negative phenomenon, because an ignorance of the pathogen, especially in younger children, leads to an unnecessary antibiotic therapy – often with antibiotics to which Campylobacter strains are resistant. In addition, epidemiological investigation aims to find the source of infection, which in turn prevents further spread

of infection. The aim of the study was a retrospective analysis of the clinical course of Campylobacter infection in children according to the age and associated infections. The retrospective analysis included 71 children with positive bacteriological investigations of 1343 children tested for Campylobacter. Ku-0059436 purchase Children were LDK378 in vitro hospitalized in the Gastroenterologic Unit, Department of Pediatrics Medical University of Silesia in Katowice between January 2008 and December 2010. The youngest hospitalized child was 6-weeks-old, the oldest was 14-year-old, and the average age was 2 years. Most of children were boys – 42 patients (representing 58.3% of examined group). Examined patients were divided into 3 groups: the group at the age under 1-year-old – 29 children (40.8%), group

at the ages of 1–3 years – 32 children (45.1%) and group above 3-year-old – 10 children (14.1%). 18% of entire examined Miconazole group (13 children) had less than 6 months and only 8 children (11.2%) was over 5 years of age. On an admission to the hospital in all patients basic laboratory tests were performed, including: the feces inoculation and Rotavirus antigen test. Inflammatory markers were analyzed – the concentration of C-reactive protein (N: <10 mg/L), leukocytosis (N: 5–12 × 103/μL) and hemoglobin concentration (N: >10.5 g/L 2–12 months of life; N: >11 g/L after 2 years of life; N: >11.5 g/L after 5 years of life). In all children with Campylobacter infection clinical symptoms and associated infections were analyzed. Microbiological tests of feces were performed in the Bacteriological

Examination Laboratory of the Regional Sanitary Epidemiological Station in Katowice. The samples were directly inoculated firstly onto Charcoal Cefoperazoned esoxycholate agar (CCDA) and next onto Columbia agar with 5% sheep blood. The incubation was done for 2–5 days at 42 °C under microaerophilic conditions. The suspected moist, translucent colonies were identified by using a Gram’s stain. The isolates were speciated by using biochemical tests such as the oxidase test, the catalase test, hippurate hydrolysis, and susceptibility to nalidixic acid. Examinations of feces viral infections (rotavirus) were performed by immunoassay in the Department of Diagnostic of Upper-Silesian Child Health Care Center. Statistical analysis was performed using the statistical software MedCalc.