Light muscle strengthening performed during the second and third trimesters of pregnancy has minimal effect on newborn body size and overall health.
On the basis of this and other information, updated recommendations for exercise in pregnancy are suggested. (Obstet Gynecol 2011;117:1399-402) DOI: 10.1097/AOG. 0b013e31821b1f5a”
“Objective. The effect of spirometric maneuvers on exhaled nitric oxide (NO) at the constant flow rate of 50 ml/s (FENO) has been studied with equivocal results. Furthermore, the effects of spirometry on bronchial NO flux (J’aw(NO)) and alveolar NO (CA(NO)), two measurements increasingly being used in clinical and research protocols, are unknown. The aim of this study was to evaluate the effect of spirometry on FENO, J’aw(NO), and CA(NO) in adults with asthma. Methods. Forty-four adults with asthma were studied. To assess the impact of exhaled NO measurement itself selleck chemicals llc on exhaled NO values, FENO, J’aw(NO), and CA(NO) were obtained twice, at baseline and after a resting period of 10 min. Then spirometry (with or without bronchodilator) was performed followed by exhaled NO measurements at 10 min. Results. In the group with pre-bronchodilator study only (n=26), mean (95% CI) values
before spirometry were 37.3 ppb (22.2-52.4) for FENO, 2375 pl/s (1613-3137) for J’aw(NO), and 1.65 ppb (0.95-2.35) for CA(NO), compared with 35.5 ppb (21.1-49.0, p=.10), 2402 pl/s (1663-3141, https://www.selleckchem.com/products/gsk-j4-hcl.html p=.85), and 1.60 ppb (0.64-2.56, p=.87) after spirometry, respectively. Spirometry-induced changes in exhaled NO values were also not significant in the group with both pre-and post-bronchodilators (n=18). Furthermore, changes in FENO, J’aw(NO), and CA(NO) values were similar in the two groups. Conclusions. Our findings demonstrate that spirometry (with or without bronchodilator) does not induce significant changes in bronchial
NO flux or alveolar NO values. Therefore, exhaled NO values may be obtained after spirometric maneuvers.”
“The aim of this study was to investigate physiological mechanisms underlying ataxia in patients with ataxic hemiparesis. Subjects were three patients with ataxic hemiparesis, whose responsible lesion was located at the posterior limb of internal capsule (case 1), thalamus (case 2), or pre- and AZD6738 post-central gyri (case 3). Paired-pulse transcranial magnetic stimulation (TMS) technique was used to evaluate connectivity between the cerebellum and contralateral motor cortex. The conditioning cerebellar stimulus was given over the cerebellum and the test stimulus over the primary motor cortex. We studied how the conditioning stimulus modulated motor evoked potentials (MEPs) to the cortical test stimulus. In non-ataxic limbs, the cerebellar stimulus normally suppressed cortical MEPs. In ataxic limbs, the cerebellar inhibition was not elicited in patients with a lesion at the posterior limb of internal capsule (case 1) or thalamus (case 2).