Methods Study design The effects of active implementation of the

Methods Study design The effects of active implementation of the EOLD-instruments is tested using

a Randomized Controlled Trial (RCT) design. Nursing homes are randomized into three groups. Two intervention groups implement the EOLD-instruments according to the generic or the patient-specific feedback strategy, and a control group is www.selleckchem.com/screening/epigenetics-compound-library.html created to control for changes that occur over time in the nursing home setting (2005–2010) independent from feedback on quality of care [9]. Setting and study population Participating nursing homes implement the EOLD-SWC and EOLD-CAD instruments Inhibitors,research,lifescience,medical on psychogeriatric wards (almost all dementia, and patients generally stay there until death). A specially trained elderly care physician employed by the nursing home is responsible for the care, Inhibitors,research,lifescience,medical including the residents’ last stage of life [29-31]. The study population comprises family caregivers (i.e., the main contact person) of nursing home residents with dementia who died on a psychogeriatric ward. Families of residents who stayed at least 16 days of the last month of their life in the nursing home are eligible to provide written feedback. Further, potential respondents Inhibitors,research,lifescience,medical need to be able to read Dutch. The nursing home invites the family member most involved in care during the last month (usually

the same person throughout admission) to provide feedback. Power analyses and recruitment of nursing homes The power analyses were based on a minimum number of family assessments to generate feedback; Inhibitors,research,lifescience,medical from there, we calculated the number of facilities in each group, from which followed a minimum and average number of beds per facility. For the cumulative feedback strategy, a minimum of 10 to 15 feedback reports is required to generate reliable total EOLD-SWC and Inhibitors,research,lifescience,medical EOLD-CAD scores and compare with national means, and we departed from an average total of 30 feedback reports

for the complete data collection period. Further, the minimum relevant difference to be detected on the EOLD instruments before and after implementation of the feedback was 3 points. Based on three previous Dutch studies using the EOLD-SWC and EOLD-CAD instruments, we assumed an Intra Class Correlation Coefficient of 0.07 for the EOLD-CAD and 0.01 for the EOLD-SWC [9]. Additionally, when taking into account a significance level (alpha) of 0.05 and a power (beta) of 0.80, a minimum else of five nursing homes per intervention group is needed. Based on a rate of 55% for eligibility and response, each participating nursing home needs to have a minimum of 22 decedents with dementia per year, and the average across facilities should amount to 33. Assuming a quarter of the nursing home residents die each year [32], the minimum number of beds of the psychogeriatric wards of participating nursing homes is 88, and the average over all facilities should amount to 132.

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