O’Mahony unified the governance of WFH bringing together the WFH’s Executive Committee and Council, into one body, composed equally of doctors and people with a bleeding disorder. Greater access to improved products, self-treatment and prophylaxis selleck chemicals in developed countries highlighted the stark differences with developing countries. Under O’Mahony, along with WFH Executive Director Line Robillard,

VP Medical Carol Kasper, MD and Evatt the WFH focused its efforts more on the developing world, designing programmes to help countries help themselves leading to sustainable national care programmes. WFH activities also expanded to include safety and supply, data and demographics, laboratory training, humanitarian aid and capacity building for its NMOs. One major step was the introduction

of the WFH Twinning Programs in 1994–95, pairing up haemophilia organizations and treatment centres in developed countries with those in developing countries. ‘Dr. Guglielmo Mariani of Italy had the idea of ‘twinning’ a well-established BAY 57-1293 haemophilia [treatment centre] programme with a new or struggling one,’ wrote Kasper. ‘It worked so well that twinning of national haemophilia organizations was added’ [12]. Operation Access, a health care development project in Chile, represented the WFH’s first major success in achieving rapid and significant improvement in haemophilia care. The WFH brought together what came to be called the ‘winning coalition’ wherein the national patient organization carried out an educational and advocacy role, the Ministry of Health agreed to establish a national haemophilia programme, a key treater coordinated the selleck chemical project’s implementation, others received

specialized training and manufacturers donated treatment products. The WFH served as a catalyst and adviser. The lives of Chileans with haemophilia changed dramatically in 5 years and the ‘winning coalition’ was adopted as part of the WFH development strategy. Based on these early health care development projects, the essential elements for a systemic integrated model to introduce and develop sustainable national care emerged. The WFH Development Model (WFH Model) was created by Evatt, Kasper, O’Mahony, Robillard and WFH Programs Director Claudia Black. These elements, which are interdependent, comprise (i) ensuring accurate laboratory diagnosis; (ii) achieving government support for a national programme; (iii) improving the care delivery system; (iv) increasing the availability of treatment products; and (v) building a strong national patient organization [13]. A sixth element, the ability to track and report patient health outcomes, was added in 2013. When the WFH first began meeting with governments, they were asked to provide supportive data; for example, governments wanted to know how many people were affected, what treatment and care cost and how many had complications.