The consumption levels and the consumer’s weights were obtained from several sources; “The national Findiet 2007 Survey”, “The

Diet of Finnish Preschoolers” and “Finnish Nutrition Recommendations 2005” (KTL-National Public Health Institute, 2008a, KTL-National Public Health Institute, 2008b and National Nutrition Council of Finland, 2005). CH5424802 All the assessments and consumption data involved only the people who use these rice products. The ICP-MS-method for the determination of elements (lead, cadmium, chromium, nickel, copper, zinc, manganese, arsenic and selenium) has been in use in Evira for several years. It has been validated and has a flexible scope accredited status. Several independent exercises (including one done for arsenic in rice

flour during this study) have demonstrated Ibrutinib research buy its applicability for other matrices as well. The limit of detection and the limit of quantification for arsenic are 0.005 mg/kg and 0.010 mg/kg, respectively. The method uncertainty for arsenic was 18%, repeatability was 13% and reproducibility was 11%. We validated and accredited the arsenic speciation method for rice. The limit of quantification and the limit of detection for inorganic arsenic were 0.06 mg/kg and 0.03 mg/kg, respectively and the overall uncertainty of the method was 25%. The repeatability, reproducibility and trueness of the method for inorganic arsenic are summarised in Table 1. These figures reveal that the method is highly repeatable (CV 11% at the level of 0.08 – 0.11 mg/kg) and reproducibility is also good (on average CV 8%). The method trueness was determined using the test material IMEP-107, a material used in one interlaboratory comparison. No certified reference

materials are available for inorganic arsenic species of rice. The trueness of the method is very good if compared to the results achieved in interlaboratory comparison. Examples of a sample chromatogram, a standard chromatogram and a blank chromatogram are in Fig. 1. The total arsenic content of long grain rice samples analysed in this study varied from 0.11 to 0.65 mg/kg (n = 8) and the average amount Sclareol of total arsenic in long grain rice samples was 0.25 mg/kg ( Table 2). The average amount of inorganic arsenic was 0.16 mg/kg, ranging from 0.09 to 0.28 mg/kg. The relative value of the total arsenic in its inorganic forms has varied from 34 to 110%, the average being 74%. AB and MMA were not detected in any of the long grain rice samples. The arsenic species detected in the rice samples were DMA, As(III) and As(V). Both Pearson and Spearman correlation tests demonstrated a significant correlation between total and inorganic arsenic levels in long grain rice at the confidence level 95% (Pearson correlation p = 0.016, Spearman correlation p = 0.043). The total arsenic content of rice based baby food products was 0.