PCB 9 was cytotoxic at 5 mu M within 5 min of exposure, and the toxicity increased

with time and concentration. None of the other congeners showed consistent cytotoxicity. The cytotoxicity was roughly correlated Selleck A1331852 with elevations in cellular ROS levels, but not with changes in intracellular calcium. To the best of our knowledge, toxicity of lower chlorinated, more volatile congeners such as PCB 9 has not been previously studied. These observations may be taken to explain the elevated risk of cardiovascular disease previously reported among residents living near to hazardous waste sites containing PCBs. (c) 2011 Wiley Periodicals, Inc. Environ Toxicol, 2012.”
“Objective. Laparoscopic techniques for placement of peritoneal dialysis catheters are becoming increasingly popular. This study describes an one-port laparoscopic technique for insertion of peritoneal dialysis learn more catheters. Material and methods. Eighteen consecutive chronic renal failure patients underwent laparoscopic placement of Swan-neck catheters. All patients were eligible to receive local

infiltration anaesthesia and none had had a previous peritoneal catheter placed. Videoscopic monitoring was performed via a peel-away sheath through an incision near the umbilicus; a 16 Fr peel-away sheath was then inserted towards the bladder and rectum. A Swan-neck catheter was passed through the peel-away sheath into the true pelvis. A subcutaneous tunnel was created and a point in left lower quadrant was selected as the exit site of

the catheter. Results. All the catheters were successfully placed and the mean time of operation was 26.5 min (range 14-35 min). The patients were discharged 2-4 Pevonedistat cell line days following the operation. During a mean follow-up period of 10.6 months (range 6-18 months), there were no catheter-related complications, such as catheter migration, dialysate leakage, exit-site infection and bacterial peritonitis. Conclusions. One-port laparoscopic technique is a simple, safe and effective method for placement of peritoneal dialysis catheters.”
“AimTo assess the diagnostic accuracy of the ultrasonographic discrimination of benign adnexal masses.

MethodsThis was a prospective study, evaluating 245 consecutive cases using real-time gray-scale ultrasonography in a tertiary education hospital.

ResultsDiagnostic accuracy was high for simple cysts and solid masses as -values of 0.824 and 0.816 and accuracy was moderate for endometriomas, dermoid cysts and cystadenomas as -values of 0.758, 0.689 and 0.627, respectively, and low for hemorrhagic cysts as a -value of 0.587. A logistic regression model was developed using ultrasonographic characteristics of the adnexal masses.