Results: After double eyelid surgery, there were no significant differences in blink duration, peak eyelid velocity, or blink rate compared with the control group. Regarding supratarsal crease appearance, dynamic creases were created in 6 of 15 patients, whereas 9 patients showed static creases.
Conclusions: Double eyelid surgery with tarsodermal fixation does not alter lid dynamics of spontaneous eye blinking. Furthermore,
the tarsodermal fixation method, which is known to create a static crease, could also lead to the development of a dynamic crease.”
“Aims: Homocysteine upregulates expression of adhesion molecules on endothelial cells which recruits NCT-501 www.selleckchem.com/products/azd2014.html leukocytes and initiates atherosclerosis. Endothelial cells in hyperhomo-cysteinemic patients are continuously
exposed to high levels of homocysteine. This study exposed adult endothelial cells and endothelial cells from immune naive foetal tissue to homocysteine chronically and studied effects on cellular adhesion molecule expression under static and flow conditions.
Methods: Human umbilical vein endothelial cells (HUVEC) and human saphenous vein endothelial cells (HSVEC) were cultured in medium containing 1 mM DL-homocysteine or L-cysteine for 5-9 days. Proliferation was assessed. Cells were subjected to flowing neutrophils and numbers of tethered, rolled fixed and transmigrated neutrophils on endothelial cells were counted and compared to controls. Immunofluorescence staining with antibodies against Intercellular adhesion molecule-1 (ICAM-1), E-selectin and P-selectin were used to quantify expression.
Results: Chronic
treatment with 1 mM homocysteine inhibited proliferation of HUVEC and HSVEC. Homocysteine treated cells showed significantly increased expression of ICAM-1, E-selectin and to a lesser extent P-selectin. In both cell types, homocysteine significantly increased interactions ACY-241 price between neutrophils and endothelial cells under flow conditions (p < 0.05) while cysteine had no effect.
Conclusion: Endothelial cells from adult and immune naive foetal tissue showed similar responses to chronic treatment with homocysteine. (C) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.”
“Morbid obesity is a disease of increasing prevalence. Diet and exercise are not effective for excess weight loss (EWL) in most patients; therefore, different bariatric surgery procedures based in restriction or malabsorption, or a combination of both, i.e., the Roux-en-Y gastric by-pass (RYGBP) hybrid operation, have been established. Here, we report the outcome of a modified RYGBP operation in 565 obese patients.